N&N Vitamin D3 + K2 Liquid 30 ml

N&N Vitamin D3 + K2 Liquid 30 ml is a food supplement that offers a liquid form of two fat-soluble micronutrients with complementary action: vitamin D3 (cholecalciferol) and vitamin K2 in the form of menaquinone-7 (MK-7). This combination is designed to optimize calcium utilization in the body, promoting its deposition in bone and reducing the risk of deposition in soft tissues, such as the arterial wall, a relevant factor for cardiovascular health.

Vitamin D3 is involved in regulating calcium and phosphorus metabolism and bone mineralization. Vitamin K2 (MK-7) acts as a cofactor in the carboxylation of vitamin K-dependent proteins, such as osteocalcin and vascular matrix Gla protein, which regulate calcium incorporation into the bone matrix and prevent ectopic calcification. Clinical studies and systematic reviews indicate that combined administration of D3 and K2 often leads to improvements in bone health markers (e.g., increased osteocalcin carboxylation) and may be associated with a reduction in vascular calcification parameters in selected populations, although results vary depending on the dose, duration, and population studied.

The liquid formulation facilitates precise dosing (0.5 ml as the recommended daily dose according to the label), its absorption when administered with a meal containing fat, and the adaptation of the dosage regimen for pediatric or geriatric patients when necessary. The vehicle is medium-chain triglycerides from coconut (MCT), with no declared palm oil, which improves the solubility and absorption of these fat-soluble vitamins. The formulation is gluten- and lactose-free.

A supplement for individuals with low sun exposure, documented vitamin D deficiency or insufficiency, older adults at risk of bone loss, postmenopausal women, athletes with high bone demands, and those following a balanced nutrition plan seeking to support bone and cardiovascular health. Supplementation can be combined with other nutritional supplements (magnesium, collagen, vitamin C, multivitamins), always evaluating interactions and individual needs.

Administration should be adjusted to the indicated dose and medical recommendations. The combined use of D3 and K2 is supported by clinical evidence suggesting synergy for bone and vascular health; however, the magnitude of the effect depends on the dose and the baseline vitamin status. Patients undergoing anticoagulant therapy (e.g., warfarin) require prior medical evaluation, as vitamin K modifies the activity of these drugs. Excess vitamin D can cause hypercalcemia; therefore, monitoring is necessary during prolonged treatment or in the presence of conditions such as hypercalcemia, hypercalciuria, or granulomatous diseases. The usual cycle duration can be set at 30–90 days, depending on the objective and clinical parameters, with periodic monitoring.

This product has no pronounced taste due to its oil base. The 30 ml bottle provides multiple doses (0.5 ml/day). Store in a cool, dry place, protected from light. Keep out of reach of children.

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