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Intensive serum for acne-prone skin - 30 ml
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  • Intensive serum for acne-prone skin - 30 ml

Avene Cleanance Comedomed Intensive Serum 30 ml

Ultra-concentrated intensive serum for acne-prone skin. Laser-like formula (30% actives) that reduces imperfections and marks, regulates excess sebum, tightens pores, and provides 24-hour hydration. Serum texture, matte finish, and compatible with facial care routines.

30 ml (pump bottle).

€27.76 €32.66 - 15%
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Avene Cleanance Comedomed Intensive Serum 30 ml
All product information

The intensive serum combines laser-inspired technology with selected dermatological actives to target the genesis of comedones and visible imperfections. The ultra-concentrated formula (30% active ingredients) integrates Comedoclastin™ (25%) to act on microcomedones, glycolic acid (3%) with a keratolytic effect that exfoliates and smooths the skin surface, and a pro-collagen cocktail made of ascorbyl glucoside and bakuchiol (2%) that contributes to skin redensification and improvement of marks. Avène thermal water provides soothing properties and contributes to skin comfort after gentle chemical exfoliation.

Texture and sensory: lightweight serum with quick absorption and a matte finish, suitable as a base before makeup. Non-comedogenic and formulated to minimize greasy feeling, facilitating its integration into routines that include facial moisturizer, facial sun protection, and other cosmetics (makeup, natural makeup). Can be used on the face, neck, and décolleté; not indicated for extensive body application.

Indications and results: designed for acne-prone, oily, or combination skin that presents imperfections, enlarged pores, and post-inflammatory marks. Suitable for teenagers (from 12 years) and adults. Improvements in skin texture and reduction of shine are usually noticeable in the first weeks; reduction of marks and redensification require several weeks of continuous use (typically 2–8 weeks depending on individual response). Maintains hydration for up to 24 hours, allowing it to be combined with moisturizers in daily routines.

Compatibility and combination: formulated to integrate with Cleanance range cleansers and facial sunscreens. The presence of glycolic acid increases photosensitivity; therefore, combining it with sunscreen is essential in the daytime routine. Can be combined with stable vitamin C and enriched moisturizers; caution when associating with other intense exfoliants or treatments with retinoids/strong acids to avoid excessive irritation. Dermatologically tested.

Positioning in the beauty routine: acts as a specific treatment within facial care and treatments for acne-prone skin. Provides a base compatible with makeup and cosmetic products, and can be part of a routine that includes anti-spot cream, wrinkle cream, or the best anti-wrinkle cream according to needs. Does not replace prescribed medical treatments for severe forms of acne.

Practical presentation: 30 ml bottle in serum pump format, designed for topical and prolonged use.

Our Online Pharmacy offers free shipping to all of Spain and the Andalusian community, including Almería, Cádiz, Córdoba, Granada, Huelva, Jaén, Málaga and Seville.

  • Acts on microcomedones to limit the appearance of new blemishes thanks to Comedoclastin™ (25%).
  • Gentle chemical exfoliation with 3% glycolic acid that improves skin texture and tone uniformity.
  • Pro-collagen cocktail (ascorbyl glucoside + bakuchiol 2%) that redensifies and improves post-inflammatory marks.
  • Reduction of excess sebum and mattifying effect, favoring a finish compatible with makeup.
  • Hydration for up to 24 hours that prevents tightness after exfoliation.
  • Non-comedogenic formula and dermatologically tested, suitable for oily, combination, and acne-prone skin.
  • Quick-absorbing serum format ideal as a base for cosmetics and facial sun protection.

What type of skin is it indicated for?

Preferably indicated for acne-prone, oily, or combination skin. The formula with glycolic acid requires assessing tolerance in sensitive skin.

In which areas can it be applied?

Designed for use on the face; can also be applied to the neck and décolleté. Not formulated for use on mucous membranes or for full body application.

From what age can it be used?

Suitable for teenagers from 12 years and adults.

When are results noticeable?

Mattifying effect and feeling of more uniform texture from the first applications; improvement of imperfections and marks visible in weeks, typically between 2 and 8 weeks depending on individual response.

Can it be combined with other treatments like vitamin C or retinoids?

Compatible with stable vitamin C and moisturizers; caution when combining with other intense exfoliants or retinoids due to the risk of irritation. Adjust frequency or consult a professional if using concomitant active treatments.

Is it non-comedogenic and dermatologically tested?

Non-comedogenic and formulated under dermatological control.

Can it be used before makeup?

Yes; serum texture and matte finish facilitate its use as a makeup or natural makeup base.

Is it safe during pregnancy and breastfeeding?

In case of pregnancy or breastfeeding, it is advisable to consult a healthcare professional to assess the appropriateness, especially if there are concomitant topical or systemic treatments.

Apply morning and night on clean skin (preferably using a Cleanance range cleanser). Dispense 1–2 pumps and distribute evenly on the face, neck, and décolleté. In daytime routine, complement with broad-spectrum facial sun protection. For sensitive skin, space applications or alternate nights until tolerance is confirmed. Suitable for combined use with facial moisturizer according to comfort and barrier protection needs.

  • The presence of glycolic acid increases photosensitivity; daily use of facial sun protection after application in the daytime routine is essential.
  • Avoid contact with eyes and mucous membranes; in case of contact, rinse with plenty of water.
  • Do not apply on irritated skin, open wounds, or after aggressive dermatological procedures without professional supervision.
  • When starting treatment, redness or slight peeling may occur; if the reaction is intense or persistent, discontinue the product and consult a specialist.
  • Caution when combining with other exfoliants, chemical peels, or isotretinoin therapies; consult a doctor for systemic acne treatments.
  • Check the complete list of ingredients in case of a history of allergy to specific components.
  • Consult a healthcare professional in case of pregnancy or breastfeeding.

30 ml (pump bottle).

  • Comedoclastin™ 25%: patented plant active that acts on microcomedones and limits the reappearance of new imperfections.
  • Glycolic acid 3%: chemical exfoliant with keratolytic action that improves texture and uniformity.
  • Ascorbyl glucoside + Bakuchiol 2%: pro-collagen combination for redensification and improvement of marks.
  • Avène thermal water: soothing ingredient that restores skin comfort.
  • Non-comedogenic formula with a total percentage of dermatological actives close to 30%.

Use it also with…

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